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Cavitation mediated rat lung bioeffects from diagnostic ultrasound

Abstract:

Several animal models have exhibited petechial hemorrhage in the lung within the current FDA output limit of diagnostic ultrasound systems. To elucidate the mechanism of damage, seven rat lungs were simultaneously exposed or sham exposed in vivo to 6‐MHz pulsed Doppler ultrasound and interrogated with a confocally aligned 30‐MHz active cavitation detector (ACD) [R. A. Roy, S. Madanshetty, and R. E. Apfel, J. Acoust. Soc. Am. 20, 2451–2455 (1990)]. The right lung lobes of four 200 g rats were ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1121/1.4744613

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Oxford college:
Harris Manchester College
Role:
Author
Publisher:
Acoustical Society of America Publisher's website
Journal:
Journal of the Acoustical Society of America Journal website
Volume:
109
Issue:
5
Host title:
Journal of the Acoustical Society of America
Publication date:
2001-06-05
DOI:
EISSN:
1520-8524
ISSN:
0001-4966
Source identifiers:
959473
Keywords:
Pubs id:
pubs:959473
UUID:
uuid:4d95f0bb-f62c-47b7-99a9-ba72263e3c03
Local pid:
pubs:959473
Deposit date:
2019-01-14

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