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Thesis

Vertex model approaches to epithelial tissues in developmental systems

Abstract:

The purpose of this thesis is to develop a vertex model framework that can be used to perform computational experiments related to the dynamics of epithelial tissues in developmental systems. We focus on three example systems: the Drosophila wing imaginal disc, the Drosophila epidermis and the visceral endoderm of the mouse embryo. Within these systems, key questions pertaining to size-control mechanisms and coordination of cell migration remain unanswered and are amenabl...

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Institution:
University of Oxford
Research group:
Centre for Mathematical Biology
Oxford college:
Hertford College
Department:
Mathematical,Physical & Life Sciences Division - Mathematical Institute
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:4d19f232-764c-4e27-bca9-d2ede0ec2db9
Local pid:
ora:6515

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