Journal article
Intravascular haemolysis in severe Plasmodium knowlesi malaria: association with endothelial activation, microvascular dysfunction, and acute kidney injury
- Abstract:
-
Plasmodium knowlesi occurs throughout Southeast Asia, and is the most common cause of human malaria in Malaysia. Severe disease in humans is characterised by high parasite biomass, reduced red blood cell deformability, endothelial activation and microvascular dysfunction. However, the roles of intravascular haemolysis and nitric oxide (NO)-dependent endothelial dysfunction, important features of severe falciparum malaria, have not been evaluated, nor their role in acute kidney injury (AKI). I...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Wellcome Trust
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Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Emerging Microbes and Infections Journal website
- Volume:
- 7
- Publication date:
- 2018-06-06
- Acceptance date:
- 2018-05-08
- DOI:
- EISSN:
-
2222-1751
- Pmid:
-
29872039
Item Description
- Language:
- English
- Pubs id:
-
pubs:857572
- UUID:
-
uuid:4ab95a16-9d8d-4526-8148-36252c46a851
- Local pid:
- pubs:857572
- Source identifiers:
-
857572
- Deposit date:
- 2018-07-05
Terms of use
- Copyright holder:
- Barber et al
- Copyright date:
- 2018
- Notes:
-
© The Authors 2018. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction
in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if
changes were made
- Licence:
- CC Attribution (CC BY)
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