Journal article : Review
Morphogens and growth factor signalling in the myeloma bone-lining niche
- Abstract:
-
Multiple myeloma is a malignancy caused by the clonal expansion of abnormal plasma cells. Myeloma cells have proven to be incredibly successful at manipulating their microenvironment to promote growth and to evade modern therapies. They have evolved to utilise the integral signalling pathways of the bone and bone marrow to drive disease progression. The bone marrow is often described in the context of a single structure that fills the bone cavity and supports normal haematopoiesis. However, w...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Blood Cancer UK
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Bibliographic Details
- Publisher:
- Springer Publisher's website
- Journal:
- Cellular and Molecular Life Sciences Journal website
- Volume:
- 78
- Issue:
- 9
- Pages:
- 4085-4093
- Publication date:
- 2021-02-11
- Acceptance date:
- 2021-01-16
- DOI:
- EISSN:
-
1420-9071
- ISSN:
-
1420-682X
- Pmid:
-
33570672
Item Description
- Language:
- English
- Keywords:
- Subtype:
- Review
- Pubs id:
-
1161217
- Local pid:
- pubs:1161217
- Deposit date:
- 2021-12-03
Terms of use
- Copyright holder:
- Morris and Edwards.
- Copyright date:
- 2021
- Rights statement:
- © The Author(s) 2021. Open Access: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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