Journal article
Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases
- Abstract:
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Microbiome-wide association studies on large population cohorts have highlighted associations between the gut microbiome and complex traits, including type 2 diabetes (T2D) and obesity1. However, the causal relationships remain largely unresolved. We leveraged information from 952 normoglycemic individuals for whom genome-wide genotyping, gut metagenomic sequence and fecal short-chain fatty acid (SCFA) levels were available2, then combined this information with genome-wide-association summary...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 1.3MB)
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(Accepted manuscript, pdf, 545.8KB)
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(Accepted manuscript, pdf, 304.0KB)
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- Publisher copy:
- 10.1038/s41588-019-0350-x
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Authors
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Genetics Journal website
- Volume:
- 51
- Pages:
- 600-605
- Publication date:
- 2019-02-18
- Acceptance date:
- 2018-12-14
- DOI:
- EISSN:
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1546-1718
- ISSN:
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1061-4036
- Source identifiers:
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963674
Item Description
- Pubs id:
-
pubs:963674
- UUID:
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uuid:4a35177d-3dc5-4784-831e-9d500f1f878b
- Local pid:
- pubs:963674
- Deposit date:
- 2019-01-18
Terms of use
- Copyright holder:
- Sanna et al
- Copyright date:
- 2019
- Notes:
- © The Author(s), under exclusive licence to Springer Nature America, Inc. 2019. This is the accepted manuscript version of the article. The final version is available online from Springer Nature at: https://doi.org/10.1038/s41588-019-0350-x
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