Journal article
Chronic TNFα - driven injury delays cell migration to villi in the intestinal epithelium
- Abstract:
-
The intestinal epithelium is a single layer of cells which provides the first line of defence of the intestinal mucosa to bacterial infection. Cohesion of this physical barrier is supported by renewal of epithelial stem cells, residing in invaginations called crypts, and by crypt cell migration onto protrusions called villi; dysregulation of such mechanisms may render the gut susceptible to chronic in ammation. The impact that excessive or misplaced epithelial cell death may have on villus ce...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Accepted manuscript, pdf, 4.3MB)
-
- Publisher copy:
- 10.1098/rsif.2018.0037
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Authors
Funding
Bibliographic Details
- Publisher:
- Royal Society Publisher's website
- Journal:
- Interface Journal website
- Volume:
- 15
- Issue:
- 145
- Article number:
- 20180037
- Publication date:
- 2018-08-01
- Acceptance date:
- 2018-07-03
- DOI:
- EISSN:
-
1742-5662
- ISSN:
-
1742-5689
- Source identifiers:
-
864655
Item Description
- Pubs id:
-
pubs:864655
- UUID:
-
uuid:487ede2f-9c04-4344-b4b7-3a153c68cecd
- Local pid:
- pubs:864655
- Deposit date:
- 2018-07-06
Terms of use
- Copyright holder:
- © 2018 Daniele, et al
- Copyright date:
- 2018
- Notes:
- This is the author accepted manuscript following peer review version of the article. The final version is available online from Royal Society at: 10.1098/rsif.2018.0037
If you are the owner of this record, you can report an update to it here: Report update to this record