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Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis

Abstract:

Background: The objective of this study was to examine the relationship between common genetic variation of the ESR2 gene and osteoarthritis.

Methods: In the discovery study, the Rotterdam Study-I, 7 single nucleotide polymorphisms (SNPs) were genotyped and tested for association with hip (284 cases, 2772 controls), knee (665 cases, 2075 controls), and hand OA (874 cases, 2184 controls) using an additive model. In the replication stage ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2350-11-164

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Publisher:
BioMed Central Publisher's website
Journal:
BMC Medical Genetics Journal website
Volume:
11
Article number:
164
Publication date:
2010-11-16
Acceptance date:
2010-11-16
DOI:
EISSN:
1471-2350
Source identifiers:
107314
Language:
English
Keywords:
UUID:
uuid:48500f62-f387-4b5d-93eb-fe227c4c4c2f
Local pid:
pubs:107314
Deposit date:
2012-12-19

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