Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis
Background: The objective of this study was to examine the relationship between common genetic variation of the ESR2 gene and osteoarthritis.Expand abstract
Methods: In the discovery study, the Rotterdam Study-I, 7 single nucleotide polymorphisms (SNPs) were genotyped and tested for association with hip (284 cases, 2772 controls), knee (665 cases, 2075 controls), and hand OA (874 cases, 2184 controls) using an additive model. In the replication stage ...
- Publication status:
- Peer review status:
- Peer reviewed
(Version of record, pdf, 378.0KB)
- Publisher copy:
- Copyright holder:
- Kerkhof et al
- Copyright date:
- © 2010 Kerkhof et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- CC Attribution (CC BY)
If you are the owner of this record, you can report an update to it here: Report update to this record