Journal article
Incorporating polygenic risk into the Leicester Risk Assessment score for 10-year risk prediction of type 2 diabetes
- Abstract:
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Aims: We evaluated whether incorporating information on ethnic background and polygenic risk enhanced the Leicester Risk Assessment (LRA) score for predicting 10-year risk of type 2 diabetes.
Methods: The sample included 202,529 UK Biobank participants aged 40–69 years. We computed the LRA score, and developed two new risk scores using training data (80% sample): LRArev, which ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.2MB, Terms of use)
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- Publisher copy:
- 10.1016/j.dsx.2024.102996
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Funding
Bibliographic Details
- Publisher:
- Elsevier
- Journal:
- Diabetes and Metabolic Syndrome: Clinical Research and Reviews More from this journal
- Volume:
- 18
- Issue:
- 4
- Article number:
- 102996
- Publication date:
- 2024-03-29
- Acceptance date:
- 2024-03-25
- DOI:
- EISSN:
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1878-0334
- ISSN:
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1871-4021
- Pmid:
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38608567
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1987772
- Local pid:
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pubs:1987772
- Deposit date:
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2024-05-24
Terms of use
- Copyright holder:
- Liu et al.
- Copyright date:
- 2024
- Rights statement:
- © 2024 The Authors. Published by Elsevier Ltd on behalf of Research Trust of DiabetesIndia (DiabetesIndia) and National Diabetes Obesity and Cholesterol Foundation (N-DOC). This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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