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Journal article

SERT and uncertainty: serotonin transporter expression influences information processing biases for ambiguous aversive cues in mice

Abstract:

The long allele variant of the serotonin transporter (SERT, 5‐HTT) gene‐linked polymorphic region (5‐HTTLPR) is associated with higher levels of 5‐HTT expression and reduced risk of developing affective disorders. However, little is known about the mechanisms underlying this protective effect. One hypothesis is that 5‐HTT expression influences aversive information processing, with reduced negative cognitive bias present in those with higher 5‐HTT expression. Here we investigated this hypothes...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/gbb.12215

Authors


More by this author
Division:
MSD
Department:
Pharmacology
Oxford college:
St Hilda's College
Role:
Author
More by this author
Division:
MSD
Role:
Author
ORCID:
0000-0001-9774-3692
More by this author
Division:
MSD
Sub department:
Pharmacology
Oxford college:
University College
Role:
Author
ORCID:
0000-0001-7434-9713
Publisher:
Wiley Publisher's website
Journal:
Genes, Brain and Behavior Journal website
Volume:
14
Issue:
4
Pages:
330-336
Place of publication:
England
Publication date:
2015-03-30
Acceptance date:
2015-03-26
DOI:
EISSN:
1601-183X
ISSN:
1601-1848
Pmid:
25824641
Language:
English
Keywords:
Pubs id:
516896
Local pid:
pubs:516896
Deposit date:
2020-02-14

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