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Neuropathic pain drives anxiety behavior in mice, results consistent with anxiety levels in diabetic neuropathy patients

Abstract:

Background

Epidemiological studies in patients with neuropathic pain demonstrate a strong association with psychiatric conditions such as anxiety; however, the precipitating pathology between these symptoms remains unclear. To investigate this, we studied the effects of lifelong stress on levels of neuropathic pain–like behavior and conversely, the effects of chronic neuropathic injury on anxietylike status in male and female mice. In addition, we assayed this link in painful and...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1097/pr9.0000000000000651

Authors


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More from this funder
Grant:
083259/C/07/Z - Kings College
Boston Children’s Hospital More from this funder
Novo Nordisk Foundation More from this funder
Publisher:
Lippincott, Williams and Wilkins Publisher's website
Journal:
Pain Reports Journal website
Volume:
3
Issue:
3
Pages:
e651
Publication date:
2018-05-24
Acceptance date:
2018-03-13
DOI:
EISSN:
2471-2531
ISSN:
2471-2531
Pubs id:
pubs:859561
URN:
uri:45fcb924-1cfa-4a2a-b935-1759a3b14b33
UUID:
uuid:45fcb924-1cfa-4a2a-b935-1759a3b14b33
Local pid:
pubs:859561

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