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Hypothesis-driven science in large-scale studies: the case of GWAS

Abstract:

It is now well-appreciated by philosophers that contemporary large-scale ‘-omics’ studies in biology stand in non-trivial relationships to more orthodox hypothesisdriven approaches. These relationships have been clarified substantially by Ratti (2015); however, there remains much more to be said regarding how an important field of genomics cited in that work—‘genome-wide association studies’ (GWAS)— fits into this framework. In the present article, we propose a revision to Ratti’s framework m...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s10539-021-09823-0

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Institution:
University of Oxford
Division:
HUMS
Department:
Philosophy Faculty
Oxford college:
Pembroke College
Role:
Author
ORCID:
0000-0003-2226-0340
Publisher:
Springer Publisher's website
Journal:
Biology and Philosophy Journal website
Volume:
36
Issue:
2021
Article number:
46
Publication date:
2021-09-19
Acceptance date:
2021-09-03
DOI:
EISSN:
1572-8404
ISSN:
0169-3867
Language:
English
Keywords:
Pubs id:
1194109
Local pid:
pubs:1194109
Deposit date:
2021-09-15

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