Journal article
Clinical implications of Plasmodium resistance to atovaquone/proguanil: a systematic review and meta-analysis
- Abstract:
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Background: Atovaquone/proguanil, registered as Malarone®, is a fixed-dose combination recommended for first-line treatment of uncomplicated Plasmodium falciparum malaria in non-endemic countries and its prevention in travellers. Mutations in the cytochrome bc1 complex are causally associated with atovaquone resistance. Methods: This systematic review assesses the clinical efficacy of atovaquone/proguanil treatment of uncomplicated malaria and examines the extent to which codon 268 mutation...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 695.7KB)
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(Version of record, docx, 55.3KB)
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- Publisher copy:
- 10.1093/jac/dkx431
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Authors
Funding
+ European Union
More from this funder
Grant:
SeventhFramework
Programmeundergrantagreement304948—NanoMal(toS.K.
H.M.S
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Journal Of Antimicrobial Chemotherapy Journal website
- Volume:
- 73
- Issue:
- 3
- Pages:
- 581–595
- Publication date:
- 2017-12-11
- Acceptance date:
- 2017-10-23
- DOI:
- EISSN:
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1460-2091
- ISSN:
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0305-7453
- Source identifiers:
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821105
Item Description
- Pubs id:
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pubs:821105
- UUID:
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uuid:4406b8e4-98ca-4b06-bf6e-b4c46e042b46
- Local pid:
- pubs:821105
- Deposit date:
- 2018-01-24
Terms of use
- Copyright holder:
- Staines et al
- Copyright date:
- 2017
- Notes:
-
Copyright © 2017 The Authors. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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