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A unified multi-level model approach to assessing patient responsiveness including; return to normal, minimally important differences and minimal clinically important improvement for patient reported outcome measures

Abstract:

OBJECTIVE:This article reviews and compares four commonly used approaches to assess patient responsiveness with a treatment or therapy (return to normal (RTN), minimal important difference (MID), minimal clinically important improvement (MCII), OMERACT-OARSI [Outcome Measures in Rheumatology-Osteoarthris Reseach Society International] (OO)) and demonstrates how each of the methods can be formulated in a multilevel modelling (MLM) framework. DESIGN:Cohort study. SETTING:A cohort of patients un...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/bmjopen-2016-014041

Authors


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Role:
Author
ORCID:
0000-0001-7452-5043
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Role:
Author
ORCID:
0000-0002-8460-1529
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Role:
Author
ORCID:
0000-0003-3353-2882
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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Population Health
Role:
Author
Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Open Journal website
Volume:
7
Issue:
7
Article number:
e014041
Publication date:
2017-07-21
Acceptance date:
2017-05-19
DOI:
ISSN:
2044-6055
Pmid:
28733296
Language:
English
Keywords:
Pubs id:
pubs:709447
UUID:
uuid:43a6f6e1-4e77-45df-bb5d-bf81a59ac429
Local pid:
pubs:709447
Source identifiers:
709447
Deposit date:
2019-03-06

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