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Mechanical and degradation properties of hybrid scaffolds for tissue engineered heart valve (TEHV)

Abstract:

In addition to biocompatibility, an ideal scaffold for the regeneration of valvular tissue should also replicate the natural heart valve extracellular matrix (ECM) in terms of biomechanical properties and structural stability. In our previous paper, we demonstrated the development of collagen type I and hyaluronic acid (HA)-based scaffolds with interlaced microstructure. Such hybrid scaffolds were found to be compatible with cardiosphere-derived cells (CDCs) to potentially regenerate the dise...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.3390/jfb12010020

Authors


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Role:
Author
ORCID:
0000-0003-0537-2551
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Institution:
University of Oxford
Division:
MSD
Sub department:
Physiology Anatomy & Genetics
Oxford college:
Pembroke College
Role:
Author
ORCID:
0000-0003-0102-5261
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Materials
Role:
Author
Publisher:
MDPI Publisher's website
Journal:
Journal of Functional Biomaterials Journal website
Volume:
12
Issue:
1
Article number:
20
Publication date:
2021-03-09
Acceptance date:
2021-03-03
DOI:
EISSN:
2079-4983
Pmid:
33803209
Language:
English
Keywords:
Pubs id:
1171444
Local pid:
pubs:1171444
Deposit date:
2021-04-15

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