Journal article
Sub-pyrogenic systemic inflammation impacts on brain and behavior, independent of cytokines.
- Abstract:
-
Systemic inflammation impacts on the brain and gives rise to behavioral changes, often referred to as 'sickness behavior'. These symptoms are thought to be mainly mediated by pro-inflammatory cytokines. We have investigated the communication pathways between the immune system and brain following sub-pyrogenic inflammation. Low grade systemic inflammation was induced in mice using lipopolysaccharide (LPS); 1-100 microg/kg to mimic aspects of bacterial infection. Changes in fever, open-field ac...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.bbi.2007.01.012
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Authors
Bibliographic Details
- Journal:
- Brain, behavior, and immunity
- Volume:
- 21
- Issue:
- 6
- Pages:
- 836-850
- Publication date:
- 2007-08-01
- DOI:
- EISSN:
-
1090-2139
- ISSN:
-
0889-1591
- Source identifiers:
-
310861
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:310861
- UUID:
-
uuid:42ac5912-7422-4406-b99c-0c09042b9f11
- Local pid:
- pubs:310861
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
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