Journal article
Genetic dissection of a Leishmania flagellar proteome demonstrates requirement for directional motility in sand fly infections
- Abstract:
-
The protozoan parasite Leishmania possesses a single flagellum, which is remodelled during the parasite’s life cycle from a long motile flagellum in promastigote forms in the sand fly to a short immotile flagellum in amastigotes residing in mammalian phagocytes. This study examined the protein composition and in vivo function of the promastigote flagellum. Protein mass spectrometry and label free protein enrichment testing of isolated flagella and deflagellated cell bodies defined a flagellar...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Pathogens Journal website
- Volume:
- 15
- Issue:
- 6
- Article number:
- e1007828
- Publication date:
- 2019-06-26
- Acceptance date:
- 2019-06-20
- DOI:
- EISSN:
-
1553-7374
- ISSN:
-
1553-7366
Item Description
- Pubs id:
-
pubs:1019786
- UUID:
-
uuid:42a18363-1e47-447d-be06-507cbf7fad6e
- Local pid:
- pubs:1019786
- Source identifiers:
-
1019786
- Deposit date:
- 2019-06-21
Terms of use
- Copyright holder:
- Beneke et al
- Copyright date:
- 2019
- Notes:
-
© 2019 Beneke et al. This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record