Journal article
Development of a multivariable gene-expression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in cross-sectional and longitudinal samples
- Abstract:
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Background Acute T-cell mediated rejection (TCMR) is usually indicated by alteration in serum-creatinine measurements when considerable transplant damage has already occurred. There is, therefore, a need for non-invasive early detection of immune signals that would precede the onset of rejection, prior to transplant damage.
Methods We examined the RT-qPCR expression of 22 literature-based genes in peripheral blood samples from 248 patients in t...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 3.2MB)
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- Publisher copy:
- 10.1016/j.ebiom.2019.01.060
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- EBioMedicine Journal website
- Volume:
- 41
- Pages:
- 571-583
- Publication date:
- 2019-03-02
- Acceptance date:
- 2019-01-31
- DOI:
- EISSN:
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2352-3964
- Source identifiers:
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980198
Item Description
- Language:
- English
- Pubs id:
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pubs:980198
- UUID:
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uuid:3f014db8-e0e3-470a-a624-c54ec1059e2e
- Local pid:
- pubs:980198
- Deposit date:
- 2019-03-06
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2019
- Notes:
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© 2019 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://
creativecommons.org/licenses/by-nc-nd/4.0/).
- Licence:
- CC Attribution (CC BY)
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