Journal article
Whole brain and regional hyperintense white matter volume and blood pressure: overlap of genetic loci produced by bivariate, whole-genome linkage analyses
- Abstract:
-
Background and Purpose— The volume of T2-hyperintense white matter (HWM) is an important neuroimaging marker of cerebral integrity with a demonstrated high heritability. Pathophysiology studies have shown that the regional, ependymal, and subcortical HWM lesions are associated with elevated arterial pulse pressure and arterial blood pressure (BP), respectively. We performed bivariate, whole-genome linkage analyses for HWM volumes and BP measurements to identify chromosomal...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1161/STROKEAHA.110.590943
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Authors
Bibliographic Details
- Publisher:
- American Heart Association Publisher's website
- Journal:
- Stroke Journal website
- Volume:
- 41
- Issue:
- 10
- Pages:
- 2137-2142
- Publication date:
- 2010-10-01
- DOI:
- EISSN:
-
1524-4628
- ISSN:
-
0039-2499
- Source identifiers:
-
445988
Item Description
- Language:
- English
- Keywords:
- Subjects:
- Pubs id:
-
pubs:445988
- UUID:
-
uuid:3bdb2da2-ab5a-49a0-abb0-dc77779968da
- Local pid:
- pubs:445988
- Deposit date:
- 2014-01-18
Terms of use
- Copyright holder:
- American Heart Association
- Copyright date:
- 2010
- Notes:
- Copyright © 2010 American Heart Association, Inc. All rights reserved. The full text of this article is not currently available in ORA.
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