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Journal article

Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis.

Abstract:

OBJECTIVE: To clarify the role of common genetic variation in the Interleukin-1β (IL1B) and Interleukin-1R antagonist (IL1RN) genes on risk of knee and hip osteoarthritis (OA) and severity of knee OA by means of large-scale meta-analyses. METHODS: We searched PubMed for articles assessing the role of IL1B and IL1RN polymorphisms/haplotypes on the risk of hip and/or knee OA. Novel data were included from eight unpublished studies. Meta-analyses were performed using fixed- and random-effects mo...

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Publication status:
Published

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Publisher copy:
10.1016/j.joca.2010.12.003

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Journal:
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society
Volume:
19
Issue:
3
Pages:
265-271
Publication date:
2011-03-01
DOI:
EISSN:
1522-9653
ISSN:
1063-4584
Source identifiers:
334991

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