Thesis
The localization and functional analysis
- Abstract:
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Nicotinic acid adenine dinucleotide phosphate (NAADP) is the most recently characterized Ca2+ mobilizing second messenger, joining inositol 1,4,5-trisphosphate (IP3) and cyclic ADP-ribose (cADPR). Previous pharmacological and biochemical studies have suggested that NAADP targets acidic Ca2+ stores rather than the ER, which releases Ca2+ in response to IP3 or cADPR. Although NAADP receptors are proposed to be distinct from those for IP3 and cADPR, the molecular identity of NAADP receptors...
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Authors
Contributors
+ Galione, A
Division:
MSD
Department:
Pharmacology
Role:
Supervisor
+ Pears, C
Division:
MSD
Department:
Pharmacology
Role:
Supervisor
Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:38955a51-7f18-4456-b916-8c896b9ee23a
- Deposit date:
- 2016-11-15
Terms of use
- Copyright holder:
- Watanabe, K
- Copyright date:
- 2011
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