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Regulatory T cells for tolerance

Abstract:

Regulatory T cells (Tregs) are critical mediators of immune homeostasis and hold significant promise in the quest for transplantation tolerance. Progress has now reached a critical threshold as techniques for production of clinical therapies are optimised and Phase I/II clinical trials are in full swing. Initial safety and efficacy data are being reported, with trials assessing a number of different strategies for the introduction of Treg therapy. It is now more crucial than ever to elucidate...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.humimm.2017.12.013

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
Role:
Author
ORCID:
0000-0002-7466-3849
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Oxford college:
Green Templeton College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
Oxford college:
Exeter College
Role:
Author
ORCID:
0000-0002-8279-7732
More from this funder
Grant:
FP7(TheOneStudy
BIO-DrIM
European Society for Organ Transplantation More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Human Immunology Journal website
Volume:
79
Issue:
5
Pages:
294-303
Publication date:
2017-12-27
Acceptance date:
2017-12-26
DOI:
EISSN:
1879-1166
ISSN:
0198-8859
Pmid:
29288698
Source identifiers:
817654
Language:
English
Keywords:
Pubs id:
pubs:817654
UUID:
uuid:3892a760-fc2b-49cf-82a4-2c1b3e2b865d
Local pid:
pubs:817654
Deposit date:
2018-11-21

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