Mutual Regulation of Epicardial Adipose Tissue and Myocardial Redox State by PPAR-γ/Adiponectin Signalling
Rationale: Adiponectin has anti-inflammatory effects in experimental models but its role in the regulation of myocardial redox state in humans is unknown. Although adiponectin is released from epicardial adipose tissue (EpAT), it is unclear whether it exerts any paracrine effects on the human myocardium.Expand abstract
Objective: To explore the cross-talk between EpAT-derived adiponectin and myocardial redox state in the human heart.
Methods and Results: EpAT and atrial myocardium were...
- Publication status:
- Peer review status:
- Peer reviewed
(Accepted manuscript, pdf, 2.1MB)
- Publisher copy:
- Copyright holder:
- American Heart Association
- Copyright date:
- © 2015 American Heart Association, Inc. Published by Lippincott, Williams and Wilkins on behalf of the American Heart Association. This is the accepted manuscript version of the article. The final version is available online from Lippincott, Williams and Wilkins at: [10.1161/CIRCRESAHA.115.307856]
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