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Journal article

Epidemiology and immune pathogenesis of viral sepsis

Abstract:

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis can be caused by a broad range of pathogens; however, bacterial infections represent the majority of sepsis cases. Up to 42% of sepsis presentations are culture negative, suggesting a non-bacterial cause. Despite this, diagnosis of viral sepsis remains very rare. Almost any virus can cause sepsis in vulnerable patients (e.g., neonates, infants, and other immunosuppressed groups). The pre...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fimmu.2018.02147

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Oxford college:
St Cross College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Paediatrics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Oxford college:
St Cross College
Role:
Author
ORCID:
0000-0001-7361-719X
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Funding agency for:
Pollard, A
Grant:
Senior Investigator
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Funding agency for:
Pollard, A
Grant:
Senior Investigator
More from this funder
Grant:
ThamesValley
sClinicalResearchNetwork
SouthMidl
REspiratory Syncytial virus Consortium in EUrope More from this funder
British Research Council More from this funder
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Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Immunology Journal website
Volume:
9
Pages:
2147
Publication date:
2018-09-27
Acceptance date:
2018-08-30
DOI:
EISSN:
1664-3224
Source identifiers:
926373
Keywords:
Pubs id:
pubs:926373
UUID:
uuid:37b42f55-2fd4-44ad-ba56-b7f7a6d34a0b
Local pid:
pubs:926373
Deposit date:
2018-10-12

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