Journal article icon

Journal article

Comparison of clinical and parasitological data from controlled human malaria infection trials.

Abstract:

BACKGROUND: Exposing healthy human volunteers to Plasmodium falciparum-infected mosquitoes is an accepted tool to evaluate preliminary efficacy of malaria vaccines. To accommodate the demand of the malaria vaccine pipeline, controlled infections are carried out in an increasing number of centers worldwide. We assessed their safety and reproducibility. METHODS: We reviewed safety and parasitological data from 128 malaria-naïve subjects participating in controlled malaria infection trials condu...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0038434

Authors


More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Role:
Author
Expand authors...
Top Institute Pharma More from this funder
Dioraphte Foundation More from this funder
Wellcome Trust More from this funder
Medical Research Council More from this funder
European Vaccine Initiative More from this funder
Expand funders...
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
7
Issue:
6
Article number:
e38434
Publication date:
2012-06-11
Acceptance date:
2012-05-09
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Source identifiers:
340152

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP