Journal article
Comparison of clinical and parasitological data from controlled human malaria infection trials.
- Abstract:
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BACKGROUND: Exposing healthy human volunteers to Plasmodium falciparum-infected mosquitoes is an accepted tool to evaluate preliminary efficacy of malaria vaccines. To accommodate the demand of the malaria vaccine pipeline, controlled infections are carried out in an increasing number of centers worldwide. We assessed their safety and reproducibility. METHODS: We reviewed safety and parasitological data from 128 malaria-naïve subjects participating in controlled malaria infection trials condu...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 315.6KB)
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- Publisher copy:
- 10.1371/journal.pone.0038434
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Authors
Funding
Top Institute Pharma
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Dioraphte Foundation
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Wellcome Trust
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Medical Research Council
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European Vaccine Initiative
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 7
- Issue:
- 6
- Article number:
- e38434
- Publication date:
- 2012-06-11
- Acceptance date:
- 2012-05-09
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- Source identifiers:
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340152
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:36bc8c57-8683-4fe8-83dc-deb1c2e8f0ef
- Local pid:
- pubs:340152
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Roestenberg et al
- Copyright date:
- 2012
- Notes:
- This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.
- Licence:
- CC Attribution (CC BY)
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