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Journal article

The ontogeny, activation and function of the epicardium during heart development and regeneration

Abstract:

The epicardium plays a key role during cardiac development, homeostasis and repair, and has thus emerged as a potential target in the treatment of cardiovascular disease. However, therapeutically manipulating the epicardium and epicardium-derived cells (EPDCs) requires insights into their developmental origin and the mechanisms driving their activation, recruitment and contribution to both the embryonic and adult injured heart. In recent years, studies of various model systems have provided u...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1242/dev.155994

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
ORCID:
0000-0003-2956-0311
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Oxford college:
Jesus College
Role:
Author
ORCID:
0000-0002-9862-7332
Publisher:
Company of Biologists Publisher's website
Journal:
Development Journal website
Volume:
145
Issue:
7
Article number:
dev155994
Publication date:
2018-03-28
Acceptance date:
2018-02-22
DOI:
EISSN:
1477-9129
ISSN:
0950-1991
Pmid:
29592950
Source identifiers:
833706
Language:
English
Keywords:
Pubs id:
pubs:833706
UUID:
uuid:357154af-3090-42c8-ac50-0b0385903763
Local pid:
pubs:833706
Deposit date:
2018-04-19

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