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Effects of variations in overall treatment time on the clonogenic survival of V79-4 cells: Implications for radiosurgery

Abstract:

The importance of effects related to the repair of sublethal radiation damage as treatment duration varies, partly a function of dose-rate, is a current controversy in clinical radiosurgery. Cell survival studies have been performed to verify the importance of this effect in relation to established models.

Mammalian V79-4 cells were irradiated in vitro with γ-rays, either as an acute exposure in a few minutes, where the effects of sublethal irradiation damage repair over the period ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst Radiation Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Oxford college:
Wolfson College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst Radiation Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst Radiation Oncology
Role:
Author
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More from this funder
Funding agency for:
Hallgren, S
Publisher:
Old City Publishing Publisher's website
Journal:
Journal of Radiosurgery and SBRT Journal website
Volume:
6
Issue:
1
Pages:
1-9
Publication date:
2019-01-16
Acceptance date:
2018-12-08
EISSN:
2156-4647
ISSN:
2156-4639
Source identifiers:
953028
Keywords:
Pubs id:
pubs:953028
UUID:
uuid:3321b56a-21a5-4ded-a22b-721bf6cb71bf
Local pid:
pubs:953028
Deposit date:
2018-12-17

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