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Thesis

Fractional exhaled nitric oxide non-suppression in asthma

Abstract:

Background: Factional exhaled nitric oxide (FeNO) and blood eosinophils are biomarkers of the higher risk type-2 inflammatory phenotype in asthma.

Objectives: 1) To assess if patients who fail to suppress FeNO after monitored therapy exhibit corticosteroid resistance. 2) To translate non-suppression of type-2 biomarkers to inflammatory mediators in the airway and peripheral blood in severe asthma. 3) To develop a prototype risk scale predicting ast...

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Division:
ContEd
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Supervisor
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Funding agency for:
Hinks, T
Grant:
211050/Z/18/Z
More from this funder
Funding agency for:
Couillard Castonguay, S
Hinks, T
Pavord, I
Type of award:
MSc
Level of award:
Masters
Awarding institution:
University of Oxford

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