Journal article
Process of Assay Selection and Optimization for the Study of Case and Control Samples from a Phase IIb Efficacy Trial of a Candidate Tuberculosis Vaccine, MVA85A
- Abstract:
-
The first phase IIb safety and efficacy trial of a new tuberculosis vaccine since that for BCG was completed in October 2012. BCG-vaccinated South African infants were randomized to receive modified vaccinia virus Ankara, expressing the Mycobacterium tuberculosis antigen 85A (MVA85A), or placebo. MVA85A did not significantly boost the protective effect of BCG. Cryopreserved samples provide a unique opportunity for investigating the correlates of the risk of tuberculosis disease in this popula...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- American Society for Microbiology Publisher's website
- Journal:
- Clinical and Vaccine Immunology Journal website
- Volume:
- 21
- Issue:
- 7
- Pages:
- 1005-1011
- Publication date:
- 2014-06-30
- Acceptance date:
- 2014-05-09
- DOI:
- EISSN:
-
1556-679X
- ISSN:
-
1556-6811
Item Description
- Language:
- English
- Pubs id:
-
pubs:465040
- UUID:
-
uuid:325a4ed8-622c-436f-bd16-2d5260cc8c92
- Local pid:
- pubs:465040
- Source identifiers:
-
465040
- Deposit date:
- 2014-06-16
Terms of use
- Copyright holder:
- Harris et al
- Copyright date:
- 2014
- Notes:
- Copyright © 2014 Harris et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license.
- Licence:
- CC Attribution (CC BY)
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