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The Impact of Biologic Therapy Introduction on Hip and Knee Replacement Among Rheumatoid Arthritis Patients: An Interrupted Time Series Analysis Using the Clinical Practice Research Datalink

Abstract:

In several developed countries it has been observed that the incidence of orthopaedic surgery among rheumatoid arthritis (RA) patients has been in decline, despite a concurrent increase among non-RA patients. Whilst the introduction of biologic therapies may be an explanatory factor for the divergent trends, specific data testing this hypothesis is lacking. We set out to estimate the impact of approval and national guidance (National Institute for Health and Care Excellence (NICE) TA36) on an...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
ORCID:
0000-0002-7034-6168
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
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Publisher:
American College of Rheumatology Publisher's website
Journal:
American Conference for Rheumatology Journal website
Host title:
2016 ACR/ARHP Annual Meeting
Publication date:
2016-09-28
Acceptance date:
2016-09-02
Source identifiers:
807169
Keywords:
Pubs id:
pubs:807169
UUID:
uuid:31bb6616-bc53-4157-ac57-13aa60c00cec
Local pid:
pubs:807169
Deposit date:
2017-12-01

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