Thesis
The role of BMP signalling in HSC ontogeny
- Abstract:
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The haematopoietic stem cell (HSC) is found in the adult human bone marrow, where it gives rise to all the circulating blood cells throughout adulthood. Understanding the signalling events that programme these cells during development will improve HSC in vitro culture, their generation from embryonic stem cells or induced pluripotent stem cells, and their potential therapeutic application. HSCs bud from the floor of the dorsal aorta and seed the bone marrow via circulation. The pr...
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Funding
Bibliographic Details
- Publication date:
- 2013
- Type of award:
- DPhil
- Level of award:
- Doctoral
- URN:
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uuid:305597a8-b8cb-42ff-88fd-34b3dd5bf39b
- Local pid:
- ora:8522
Item Description
- Language:
- English
- Keywords:
- Subjects:
Terms of use
- Copyright holder:
- Stuart J Meiklejohn
- Copyright date:
- 2013
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