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Extracellular signal-regulated kinases 1/2 and their role in cardiac diseases

Abstract:

Mitogen-activated protein (MAP) kinases comprise a well-studied family of serine/threonine protein kinases involved in signal transduction pathways that control multiple cellular processes. The extracellular signal-regulated kinase (ERK1/2) cascade is a central MAP kinase pathway that transmits signals from the cell surface to substrates either in the nucleus or in the cytoplasm. The transmission of the signal through the ERK1/2 cascade is mediated by phosphorylation and activation of prot...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.14800/sp.457

Authors


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Institution:
University of Oxford
Division:
Medical Science Division
Department:
Oncology
Sub department:
CRUK/MRC OX INST Radiation Oncology
Department:
Oxford, MSD, Oncology, CRUK/MRC Ox Inst Radiation Oncology
Role:
Author
Publisher:
Smart Science and Technology Publisher's website
Journal:
Science Proceedings Journal website
Volume:
02
Pages:
1-4
Publication date:
2015-01-28
DOI:
ISSN:
2375-7795
Keywords:
Pubs id:
pubs:1011914
UUID:
uuid:2fbb6c2f-05b6-41e9-91e7-e623ee49ce31
Local pid:
pubs:1011914
Source identifiers:
1011914
Deposit date:
2019-06-12

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