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Synovial single-cell heterogeneity, zonation and interactions: a patchwork of effectors in arthritis

Abstract:

Despite extensive research, there is still no treatment that would lead to remission in all patients with rheumatoid arthritis as our understanding of the affected site, the synovium, is still incomplete. Recently, single-cell technologies helped to decipher the cellular heterogeneity of the synovium; however, certain synovial cell populations, such as endothelial cells or peripheral neurons, remain to be profiled on a single-cell level. Furthermore, associations between certain cellular stat...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/rheumatology/keab721

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Oxford college:
Wolfson College
Role:
Author
Publisher:
British Society for Rheumatology Publisher's website
Journal:
Rheumatology Journal website
Volume:
61
Issue:
3
Pages:
913-925
Publication date:
2021-09-24
Acceptance date:
2021-09-13
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
Pmid:
34559213
Language:
English
Keywords:
Pubs id:
1198006
Local pid:
pubs:1198006
Deposit date:
2022-01-17

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