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Journal article

Benefits and harms of antihypertensive treatment in low-risk patients with mild hypertension

Abstract:

Importance

Evidence to support initiation of pharmacological treatment in patients with low-risk mild hypertension is inconclusive, with previous trials underpowered to demonstrate benefit. Clinical guidelines across the world are contradictory.

Objective

Use electronic health records to examine whether treatment is safe and effective at reducing the risk of mortality and cardiovascular disease in low-risk mild hypertensives.

Design

Longitudinal co...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0002-4461-8756
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care Health Sciences
Role:
Author
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More from this funder
Funding agency for:
Sheppard, J
Grant:
NIHR-RP-R2-12-015
More from this funder
Funding agency for:
Sheppard, J
Grant:
NIHR-RP-R2-12-015
More from this funder
Funding agency for:
McManus, R
Grant:
NIHR-RP-R2-12-015
Publisher:
American Medical Association Publisher's website
Journal:
JAMA Internal Medicine Journal website
Volume:
178
Issue:
12
Pages:
1626-1634
Publication date:
2018-10-29
Acceptance date:
2018-07-18
DOI:
EISSN:
2168-6114
ISSN:
2168-6106
Pmid:
30383082
Source identifiers:
936689
Language:
English
Keywords:
Pubs id:
pubs:936689
UUID:
uuid:2ed7cf28-71d9-4c22-8c5f-a21af1e1f688
Local pid:
pubs:936689
Deposit date:
2018-11-08

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