Journal article
Detection of mixed infection from bacterial whole genome sequence data allows assessment of its role in Clostridium difficile transmission
- Abstract:
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Bacterial whole genome sequencing offers the prospect of rapid and high precision investigation of infectious disease outbreaks. Close genetic relationships between microorganisms isolated from different infected cases suggest transmission is a strong possibility, whereas transmission between cases with genetically distinct bacterial isolates can be excluded. However, undetected mixed infections-infection with ≥2 unrelated strains of the same species where only one is sequenced-potentially im...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
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(pdf, 584.2KB)
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- Publisher copy:
- 10.1371/journal.pcbi.1003059
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Authors
Funding
Wellcome Trust
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Department of Health
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Medical Research Council
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Biotechnology and Biological Sciences Research Council
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS computational biology Journal website
- Volume:
- 9
- Issue:
- 5
- Pages:
- e1003059
- Publication date:
- 2013-05-02
- DOI:
- EISSN:
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1553-7358
- ISSN:
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1553-734X
- Pubs id:
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pubs:401501
- URN:
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uri:2b40254c-3bbd-4e63-a25f-b98a962bcc9c
- UUID:
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uuid:2b40254c-3bbd-4e63-a25f-b98a962bcc9c
- Local pid:
- pubs:401501
- Paper number:
- 5
Item Description
Terms of use
- Copyright holder:
- Eyre et al.
- Copyright date:
- 2013
- Notes:
- © 2013 Eyre et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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