Population-specific HLA impact in immune control of HIV in Mexico and non-Mexican HIV infected cohorts
HIV-1 persists to be a major health problem worldwide. A prophylactic or therapeutic vaccine offers the best hope to restrain the HIV-1 epidemic, however a consistent correlate of immune protection is yet to be found.
HLA class I expression and their restricting HIV-1 specific CD8+ T cell responses have been shown to play a vital role in the control of HIV-1 infection. The interactions between HIV-1 and CD8+ T cell responses are complex and the mechanisms involved in the ...Expand abstract
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- University of Oxford
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- Juarez Molina, C; Claudia Molina
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