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Thesis

Population-specific HLA impact in immune control of HIV in Mexico and non-Mexican HIV infected cohorts

Abstract:

HIV-1 persists to be a major health problem worldwide. A prophylactic or therapeutic vaccine offers the best hope to restrain the HIV-1 epidemic, however a consistent correlate of immune protection is yet to be found.

HLA class I expression and their restricting HIV-1 specific CD8+ T cell responses have been shown to play a vital role in the control of HIV-1 infection. The interactions between HIV-1 and CD8+ T cell responses are complex and the mechanisms involved in the ...

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Institution:
University of Oxford
Division:
MSD
Department:
Paediatrics
Research group:
Goulder
Oxford college:
Wolfson College
Role:
Author

Contributors

Division:
MSD
Department:
Paediatrics
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:2a6242d2-91bf-4029-9067-a922cbf1d8e4
Local pid:
ora:9606
Deposit date:
2014-12-17

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