Thesis
Preimplantation genetic diagnosis - new methods for the detection of genetic abnormalities in human preimplantation embryos
- Abstract:
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Preimplantation genetic diagnosis (PGD) refers to the testing of embryos produced through in vitro fertilization (IVF) in order to identify those unaffected by a specific genetic disorder or chromosomal abnormality. In this study, different methodologies were examined and developed for performance of PGD. Investigation of various whole genome amplification (WGA) methods identified multiple displacement amplification as a reliable method for genotyping single cells. Furthermore, this technolog...
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Authors
Contributors
+ Wells, D
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Supervisor
Bibliographic Details
- Publication date:
- 2013
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:28611f65-7729-4293-9c3f-4fc3f0cc39d7
- Local pid:
- ora:7042
- Deposit date:
- 2013-07-18
Terms of use
- Copyright holder:
- Konstantinidis, M
- Copyright date:
- 2013
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