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Journal article : Review

Cellular stress management by caspases

Abstract:

Cellular stress plays a pivotal role in the onset of numerous human diseases. Consequently, the removal of dysfunctional cells, which undergo excessive stress-induced damage via various cell death pathways, including apoptosis, is essential for maintaining organ integrity and function. The evolutionarily conserved family of cysteine-aspartic-proteases, known as caspases, has been a key player in orchestrating apoptosis. However, recent research has unveiled the capability of these enzymes to ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ceb.2023.102314

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
ORCID:
0000-0002-8663-3794
Publisher:
Elsevier
Journal:
Current Opinion in Cell Biology More from this journal
Volume:
86
Article number:
102314
Publication date:
2024-01-11
Acceptance date:
2023-12-18
DOI:
EISSN:
1879-0410
ISSN:
0955-0674
Pmid:
38215516
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1598848
Local pid:
pubs:1598848
Deposit date:
2024-02-26

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