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The use of a large pharmacoepidemiological database to study exposure to oral corticosteroids and risk of fractures: validation of study population and results.

Abstract:

Purpose - The objective of this study was an evaluation of the sensitivity of findings of the relationship between oral corticosteroid use and the risk of fracture. We found in earlier work that the risk of fracture was significantly higher during oral corticosteroid treatment, with increases of 61% in hip and 160% in vertebral fractures.Methods - Information was obtained from the General Practice Research Database which contains medical records of general practitioners in the UK. The study i...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Pharmacoepidemiology and drug safety
Volume:
9
Issue:
5
Pages:
359-366
Publication date:
2000-09-01
DOI:
EISSN:
1099-1557
ISSN:
1053-8569
Source identifiers:
125498
Language:
English
Keywords:
Pubs id:
pubs:125498
UUID:
uuid:25de06cd-6654-417f-bd9a-0983e4a62591
Local pid:
pubs:125498
Deposit date:
2013-11-17

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