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Thesis

Cardiac stem cell therapy for infarcted rat hearts

Abstract:

Infarction irreversibly damages the heart, with formation of an akinetic scar that may lead to heart failure. Endogenous cardiac stem cells (CSCs) are a promising candidate cell source for restoring lost tissue and thereby preventing heart failure. CSCs would be most beneficial if administered soon after infarction, thus the aim of this project was to optimize CSC culture conditions to enhance their therapeutic potential for myocardial infarction. CSCs were isolated and expanded in vitro via ...

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Institution:
University of Oxford
Research group:
Cardiac Metabolism Research Group
Oxford college:
Green Templeton College
Department:
Medical Sciences Division - Physiology,Anatomy and Genetics,Department of
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:24479cf6-74ec-47f7-a0ef-92706036edac
Local pid:
ora:5850

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