Thesis
Computational studies of protein helix kinks
- Abstract:
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Kinks are functionally important structural features found in the alpha-helices of many proteins, particularly membrane proteins. Structurally, they are points at which a helix abruptly changes direction. Previous kink definition and identification methods often disagree with one another.
Here I describe three novel methods to characterise kinks, which improve on existing approaches. First, Kink Finder, a computational method that consistently locates kinks and estimates the error i...
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Authors
Contributors
+ Deane, C
Division:
MPLS
Department:
Statistics
Role:
Supervisor
+ Shi, J
Division:
MPLS
Department:
Statistics
Role:
Supervisor
Funding
+ Engineering and Physical Sciences Research Council
More from this funder
Funding agency for:
Wilman, H
Grant:
EP/G037280/1
Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:21225f0e-efed-49c6-af27-5d3fe78fa731
- Local pid:
- ora:11726
- Deposit date:
- 2015-06-24
Terms of use
- Copyright holder:
- Henry Wilman
- Copyright date:
- 2014
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