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Journal article : Review

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone fractures of the upper and lower limbs

Abstract:

Background

Open fractures of the major long bones are complex limb‐threatening injuries that are predisposed to deep infection. Treatment includes antibiotics and surgery to debride the wound, stabilise the fracture and reconstruct any soft tissue defect to enable infection‐free bone repair. There is a need to assess the effect of timing and duration of antibiotic administration and timing and staging of surgical interventions to optimise outcomes.

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
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Publisher:
Wiley Publisher's website
Journal:
Cochrane Database of Systematic Reviews Journal website
Volume:
2022
Issue:
4
Article number:
CD013555
Publication date:
2022-04-01
DOI:
EISSN:
1469-493X
Pmid:
35363374
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1250440
Local pid:
pubs:1250440
Deposit date:
2022-05-04

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