Thesis
Selection along the HIV-1 genome through the CTL mediated immune response
- Abstract:
-
During human immunodeficiency virus 1 (HIV-1) infection, the viral population is in constant battle with the host immune system. The cytotoxic T-lymphocyte (CTL) response, a branch of the adaptive immune response, is implicated in viral control and can drive viral evolution in the infected host population. Endogenous viral peptides, or ‘epitopes’, are presented to CTLs by human leukocyte antigen (HLA) class I molecules on the surface of infected cells where they may be identified as non-se...
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Authors
Contributors
+ McVean, G
Division:
MPLS
Department:
Statistics
Role:
Supervisor
+ McLean, A
Division:
MPLS
Department:
Statistics
Role:
Supervisor
Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:1cd57b15-485d-4f5a-8a1c-7702a355c597
- Local pid:
- ora:10382
- Deposit date:
- 2015-03-03
Related Items
Terms of use
- Copyright holder:
- Palmer, D
- Copyright date:
- 2014
- Notes:
- This thesis is not currently available in ORA
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