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Journal article

Placebo comparator group selection and use in surgical trials: the ASPIRE project including expert workshop

Abstract:

Background

The use of placebo comparisons for randomised trials assessing the efficacy of surgical interventions is increasingly being considered. However, a placebo control is a complex type of comparison group in the surgical setting and, although powerful, presents many challenges.

Objectives

To provide a summary of knowledge on placebo controls in surgical trials and to summarise any recommendations for designers, evaluators and funders of ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3310/hta25530

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Oxford college:
Kellogg College
Role:
Author
ORCID:
0000-0001-7884-6389
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
ORCID:
0000-0001-5940-1464
Publisher:
NIHR Journals Library Publisher's website
Journal:
Health Technology Assessment Journal website
Volume:
25
Issue:
53
Publication date:
2021-09-10
Acceptance date:
2021-06-23
DOI:
ISSN:
1366-5278
Language:
English
Keywords:
Pubs id:
1183253
Local pid:
pubs:1183253
Deposit date:
2021-06-24

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