Journal article
A randomized, double‐blind, placebo‐controlled trial of camicinal in Parkinson's disease
- Abstract:
-
Background: Delayed gastric emptying may impair ʟ-dopa absorption, contributing to motor fluctuations. We evaluated the effect of camicinal (GSK962040), a gastroprokinetic, on the absorption of ʟ-dopa and symptoms of PD.
Methods: Phase II, double‐blind, placebo‐controlled trial. Participants were randomized to receive camicinal 50 mg once‐daily (n = 38) or placebo (n = 20) for 7 to 9 days.
Results: ʟ-dopa exposure was similar...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Parkinsonfonden
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Michael J. Fox Foundation
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GlaxoSmithKline
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Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Movement Disorders Journal website
- Volume:
- 33
- Issue:
- 2
- Pages:
- 329-332
- Publication date:
- 2017-12-26
- Acceptance date:
- 2017-11-05
- DOI:
- EISSN:
-
1531-8257
- ISSN:
-
0885-3185
- Pmid:
-
29278279
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1033403
- UUID:
-
uuid:17aed29d-0b66-43e1-b06f-c86cd10b997e
- Local pid:
- pubs:1033403
- Source identifiers:
-
1033403
- Deposit date:
- 2019-07-18
Terms of use
- Copyright holder:
- Marrinan et al
- Copyright date:
- 2017
- Notes:
- © 2017 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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