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Probing multi-scale mechanical damage in connective tissues using X-ray diffraction

Abstract:

The accumulation of microstructural collagen damage following repetitive loading is linked to painful and debilitating tendon injuries. As a hierarchical, semi-crystalline material, collagen mechanics can be studied using X-ray diffraction. The aim of the study was to describe multi-structural changes in tendon collagen following controlled plastic damage (5% permanent strain). We used small angle X-ray scattering (SAXS) to interrogate the spacing of collagen molecules within a fibril, and wi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.actbio.2016.08.027

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Oxford college:
Wadham College
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Acta Biomaterialia Journal website
Volume:
45
Pages:
321–327
Publication date:
2016-08-21
Acceptance date:
2016-08-17
DOI:
EISSN:
1878-7568
ISSN:
1878-7568 and 1742-7061
Source identifiers:
640080
Keywords:
Pubs id:
pubs:640080
UUID:
uuid:178f109b-869e-46c1-b598-a1b80f28cd78
Local pid:
pubs:640080
Deposit date:
2016-08-20

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