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Thesis

Evaluation of immune correlates to TB vaccines

Abstract:

Development of an improved TB vaccine is hindered by the lack of a correlate of protection. Efficacy of TB vaccines in humans can only be assessed by expensive and time consuming trials within TB endemic areas, which are limited; therefore, it is critical that vaccines with the greatest potential to protect are selected for these trials. Mycobacterial growth inhibition assays (MGIAs) have been developed with the hope that these in vitro functional assays will correlate with protec...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
Jenner Institute
Oxford college:
Wolfson College
Role:
Author

Contributors

Division:
MSD
Department:
NDM
Role:
Supervisor
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:1785050f-c963-40f9-8b97-ad008b9a769d
Deposit date:
2016-11-15

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