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Association between hemagglutinin stem-reactive antibodies and influenza A/H1N1 virus infection during the 2009 pandemic.

Abstract:

The discovery of influenza virus broadly neutralizing (BrN) antibodies prompted efforts to develop universal vaccines. Influenza virus stem-reactive (SR) broadly neutralizing antibodies have been detected by screening antibody phage display libraries. However, studies of SR BrN antibodies in human serum, and their association with natural infection, are limited. To address this, pre- and postpandemic sera from a prospective community cohort study in Vietnam were assessed for antibodies that i...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/jvi.00093-16

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Oxford college:
Wolfson College
Role:
Author
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Publisher:
American Society for Microbiology Publisher's website
Journal:
Journal of Virology Journal website
Volume:
90
Issue:
14
Pages:
6549-6556
Publication date:
2016-05-01
Acceptance date:
2016-04-24
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
Pmid:
27170747
Source identifiers:
623135

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