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Journal article

Seronegative antibody‐mediated neurology after immune checkpoint inhibitors

Abstract:

Checkpoint inhibitor medications have revolutionized oncology practice, but frequently induce immune‐related adverse events. During autoimmune neurology practice over 20 months, we prospectively identified four patients with likely antibody‐mediated neurological diseases after checkpoint inhibitors: longitudinally extensive transverse myelitis, Guillain–Barré syndrome, and myasthenia gravis. All patients shared three characteristics: symptoms commenced 4 weeks after drug administration, respo...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/acn3.547

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
Role:
Author
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Funding agency for:
Irani, S
Grant:
MS-Research Society Award
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Grant:
Oxford Biomedical Research Centre
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Funding agency for:
Beeson, D
Grant:
MR/M006824
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Funding agency for:
Rinaldi, S
Grant:
MR/P008399/1
More from this funder
Funding agency for:
Irani, S
Grant:
MS-Research Society Award
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Publisher:
Wiley Publisher's website
Journal:
Annals of Clinical and Translational Neurology Journal website
Volume:
5
Issue:
5
Pages:
640-645
Publication date:
2018-03-25
Acceptance date:
2018-02-13
DOI:
EISSN:
2328-9503
Pubs id:
pubs:825123
UUID:
uuid:15100985-cf4d-4ef0-8a92-13b92df8ef69
Local pid:
pubs:825123
Deposit date:
2018-02-18

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