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Lamprey neural Helix-Loop-Helix (HLH) genes and the evolution of the vertebrate nervous system

Abstract:

Transcription factors of the helix-loop-helix (HLH) gene family are widespread in the animal kingdom. Among them, members of HLH subfamilies such as ASCL, Neurogenin, NeuroD, COE, Atonal, Oligo, NSCL, Hairy/E(spl) and Hey (here referred to as neural HLH genes) have been shown to be fundamental for the development of the nervous system. They are expressed at different time periods of neuronal differentiation, from the specification of ectoderm towards a neural lineage, to ...

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Institution:
University of Oxford
Oxford college:
St Anne's College
Department:
Mathematical,Physical & Life Sciences Division - Zoology
Role:
Author

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Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:107e31ad-9183-4b07-842b-d01e27a4c9e6
Local pid:
ora:10086

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