Thesis
Adaptive changes of influenza virus A/H5N1 neuraminidase in vitro and in vivo
- Abstract:
-
H5N1 adaptation process is thought to primarily involve in changes of the 2 main glycoproteins of influenza virus: hemagglutinin HA, responsible for viral entry via binding with host cell receptors, and neuraminidase NA, a receptor destroying enzyme, promoting release of newly formed virions and preventing their self-aggregation. With their opposing roles in viral replication cycle, one rational assumption is that influenza virus needs to maintain a balance between these 2 proteins activit...
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Authors
Contributors
+ van Doorn, R
Division:
MSD
Department:
NDM
Role:
Supervisor
+ Bryant, J
Division:
MSD
Department:
NDM
Role:
Supervisor
+ de Jong, M
Division:
MSD
Department:
NDM
Role:
Supervisor
Funding
Bibliographic Details
- Publication date:
- 2014
- Type of award:
- MSc by Research
- Level of award:
- Masters
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:1037fb1a-c4a1-4bd4-8b5a-7d7add49e879
- Local pid:
- ora:11353
- Deposit date:
- 2015-05-01
Terms of use
- Copyright holder:
- Le Nguyen, T
- Copyright date:
- 2014
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